Description

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively binds the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor. In experimental models, Ipamorelin activates Gq/PLC-dependent calcium signaling pathways that stimulate growth hormone release while demonstrating minimal activity on other pituitary hormones, including ACTH, prolactin, FSH, LH, TSH, and cortisol. Due to its high receptor selectivity, Ipamorelin is widely utilized in research investigating somatotropic signaling specificity, pituitary receptor pharmacology, and peptide-mediated regulation of musculoskeletal growth and tissue repair.

For research use only. Not for human consumption.

References:
Svensson J et al., J Endocrinol Invest, 1998 21(9):692–699
Bowers CY et al., Ann NY Acad Sci, 1998 865:244–249
Raun K et al., Eur J Endocrinol, 1998 139(5):552–561